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	Provedor de dados BJID (1) BJMBR (1) Autor Andrade,Agnes Carvalho (1) Araújo,Iguaracyra (1) Arruda,Maria da Gloria Bomfim (1) Bezerra,C.N.A. (1) Bittencourt,Achiléa L. (1) Hiraki,Y. (1) Melo,N.B. (1) Rebouças,N.A. (1) Requião,Cristiane (1) Sales,M.M. (1) Mais... Palavra-chave Adult T-cell leukemia/lymphoma (2) HTLV-1 infection (1) Hodgkin-like ATLL (1) Human T-lymphotropic virus 1 (1) Leukemia (1) Oligoclonal bands (1) Polymerase chain (1) Pulmonary tuberculosis (1) Reaction (1) T-cell receptor beta chain (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/report (1) Ano 2017 (1) 2005 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Identification of clonally rearranged T-cell receptor beta chain genes in HTLV-I carriers as a potential instrument for early detection of neoplasia BJMBR Sales,M.M.; Bezerra,C.N.A.; Hiraki,Y.; Melo,N.B.; Rebouças,N.A.. We analyzed the genetic recombination pattern of the T-cell receptor beta-chain gene (TCR-beta) in order to identify clonal expansion of T-lymphocytes in 17 human T-lymphotropic virus type I (HTLV-I)-positive healthy carriers, 7 of them with abnormal features in the peripheral blood lymphocytes. Monoclonal or oligoclonal expansion of T-cells was detected in 5 of 7 HTLV-I-positive patients with abnormal lymphocytes and unconfirmed diagnosis by using PCR amplification of segments of TCR-beta gene, in a set of reactions that target 102 different variable (V) segments, covering all members of the 24 V families available in the gene bank, including the more recently identified segments of the Vbeta-5 and Vbeta-8 family and the two diversity beta segments.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Human T-lymphotropic virus 1; Leukemia; Oligoclonal bands; T-cell receptor beta chain; Polymerase chain; Reaction; Adult T-cell leukemia/lymphoma. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000500006 Prolonged lymphocytosis as the first manifestation of Hodgkin-like adult T-cell leukemia/lymphoma BJID Bittencourt,Achiléa L.; Andrade,Agnes Carvalho; Requião,Cristiane; Arruda,Maria da Gloria Bomfim; Araújo,Iguaracyra. Abstract Hodgkin-like ATLL is a rare variant of adult T-cell leukemia/lymphoma (ATLL), a disease caused by human T-cell lymphotropic virus type-1 (HTLV-1). At admission, a 46-year-old female presented with lymphadenomegaly, lymphocytosis, slight elevation of LDH blood level, and acid-alcohol resistant bacilli in sputum and was being treated for pulmonary tuberculosis (Tb). She had lymphocytosis in the previous 20 months. Serology for HTLV-1 was positive. Lymph node was infiltrated by medium-sized lymphocytes with scattered Hodgkin and Reed-Sternberg-like cells CD30+, CS1-4+, and CD79a+. Background cells were CD4+ and CD25+. A clinical diagnosis of favorable chronic ATLL was given. She was treated with chemotherapy but later progressed to acute ATLL and... Tipo: Info:eu-repo/semantics/report Palavras-chave: Adult T-cell leukemia/lymphoma; HTLV-1 infection; Pulmonary tuberculosis; Hodgkin-like ATLL. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100119 Registros recuperados: 2 Primeira ... 1 ... Última

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